The first step in a successful search is to break your question down into key concepts. We recommend that you then search on each concept individually. For example, let's say you wanted to know about pain caused by rheumatoid arthritis. What's the benefit in doing separate searches (one for "pain" and the other for "rheumatoid arthritis")? Why not just search on "rheumatoid arthritis pain"?
One reason is that PubMed uses a controlled vocabulary (subject headings) to help refine your search. When you search on "rheumatoid arthritis" using the MeSH drop-down box, you are presented with subject headings to choose from. This allows you to retrieve all articles that were tagged with the subject heading "rheumatoid arthritis." Doing a separate search on "pain" allows you to access all articles in which pain is a major subject. Combining the two searches means that you'll get articles in which both "rheumatoid arthritis" and "pain" are major topics.
If you search for "rheumatoid arthritis pain," PubMed will try to find a single subject heading that addresses both concepts. When no such subject heading is found, PubMed will give you a scattered list of terms that are somewhat related.
The search screen below is the starting point for all PubMed database searches. Once you have decided on the keywords you want to search, type one of your keywords into the search bar. We recommend you use MeSH terms, accessed by the drop-down box to the left. More information on MeSH can be found via the MeSH tab on the left.
Let's say that you want to know the connection between high blood pressure and varicose veins.
Now you need to find articles that pertain to both hypertension and varicose veins. We'll do this by combining the searches. To find your searches, click the Advanced link beneath the search box.
In Advanced Search, you will see your search history. In this case, we want articles that pertain to hypertension AND varicose veins. Clicking the Add button next to each search will add it to the search builder, which defaults to AND. Click "Search" beneath the search builder. A search for articles that pertain to both of these subjects yields 111 citations.
AND, OR, NOT - often called Boolean Operators, those are the choices for combining search terms. For more information, see the guide AND, OR and NOT - Which to Choose? at the left of this page.
We can refine these 111 results by using the filters to the left. For example, by choosing Humans as the subject, and adding English as the language (using the "Show additional filters" option at the bottom of the filters list), we fine-tune our results to 25 articles. For more help using filters in PubMed, click the "Filters" tab to the left.
That's it! You now have 25 citations that match your search criteria. At this point, you probably want to add your citations to RefWorks or another citation management system. For help adding your citations to RefWorks, click the Saving PubMed Results to RefWorks tab to the left.
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